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SMN2 抗体

(Survival of Motor Neuron 2, Centromeric (SMN2))
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. While mutations in the telomeric copy are associated with spinal muscular atrophy, mutations in this gene, the centromeric copy, do not lead to disease. This gene may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The full length protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Four transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Sep 2008].
SMN2 抗体  (AA 1-282) SMN2 抗体  (AA 1-282) SMN2 抗体 (AA 1-282) (ABIN948481)

SMN2 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B11-2A9 unconjugated

SMN2 抗体  (AA 16-251) SMN2 抗体  (AA 16-251) SMN2 抗体 (AA 16-251) (ABIN7435538)

SMN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

SMN2 抗体  (AA 1-197) SMN2 抗体  (AA 1-197) SMN2 抗体 (AA 1-197) (ABIN6148134)

SMN2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

SMN2 抗体 by 适用

Find SMN2 抗体 for a variety of species such as anti-Human SMN2, anti-Mouse SMN2, anti-Dog SMN2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find SMN2 抗体 validated for a specific application such as WB, IF, IHC, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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SMN2 抗体 by 抗原表位

Find SMN2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SMN2 抗体 by 克隆形成能力

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SMN2 抗体 by 克隆

Find SMN2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Popular SMN2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN948481
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7435538
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN6148134
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7256164
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948478
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN6148135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN562921
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IP
Validations
  • (1)
Cat. No. ABIN948480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN948479
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Goat, Horse, Human, Mouse, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN2789459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA
Validations
Cat. No. ABIN2363222
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF/ICC
Validations
Cat. No. ABIN6337664
Quantity 1 mL
Datasheet Datasheet

Aliases for SMN2 抗体

survival of motor neuron 2, centromeric (SMN2) 抗体
survival of motor neuron 2, centromeric L homeolog (smn2.L) 抗体
BCD541 抗体
bcd541 抗体
C-BCD541 抗体
c-bcd541 抗体
gemin-1 抗体
GEMIN1 抗体
smn2 抗体
SMNC 抗体
smnc 抗体
TDRD16B 抗体
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