SMPD3 抗体 (AA 184-553)
Our Local Distributor
北京 101111
Quick Overview for SMPD3 抗体 (AA 184-553) (ABIN7600377)
抗原
See all SMPD3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 184-553
-
原理
- Anti-SMPD3 Antibody
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
预测反应
- Human SMPD3 shares 88.9% amino acid (aa) sequence identity with both mouse,rat SMPD3.
-
产品特性
- Anti-SMPD3 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SMPD3 recombinant protein (Position: F184-D553). Human SMPD3 shares 88.9% amino acid (aa) sequence identity with both mouse and rat SMPD3.
-
亚型
- IgG
-
-
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibody
SMPD3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 401-655) antibodySMPD3 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibodySMPD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 137-165), (N-Term) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal RB39878 unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 416-655) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (Middle Region) antibodySMPD3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
-
别名
- SMPD3
-
背景
-
Background: Sphingomyelin phosphodiesterase 3 is an enzyme that in humans is encoded by the SMPD3 gene. SMPD3 (Sphingomyelin phosphodiesterase 3, also Neutral sphingomyelinase 2/nSMase2) is a 69-74 kDa member of the neutral sphingomyelinase family of enzymes. It is a monomeric Golgi/plasma membrane enzyme that converts sphingomyelin (a plasma membrane lipid) into ceramide and phosphorylcholine. This generates second messenger components that participate in signal transduction. Human SMPD3 is a two transmembrane, 655 amino acids molecule. It contains an N-terminal luminal segment (aa 1-10), a cytoplasmic region (aa 32-64), and one catalytic domain (aa 340-646). Phosphorylation increases its MW to 78 kDa in SDS-PAGE. There is one potential isoform that possesses an Asn substitution for aa 569-587. Over aa 2-655, human SMPD3 shares 91 % aa sequence identity with mouse SMPD3.
Gene Full Name: sphingomyelin phosphodiesterase 3
-
分子量
- 75 kDa
-
基因ID
- 55512
-
UniProt
- Q9NY59
-
途径
- Hormone Transport
抗原
-
