SMG8 抗体
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).
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Aliases for SMG8 抗体
SMG8, nonsense mediated mRNA decay factor (SMG8) 抗体smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg8) 抗体
Protein smg-8 (smg-8) 抗体
1200011M11Rik 抗体
C17orf71 抗体
C19H17orf71 抗体
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