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SMCR8 抗体

(Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8))
Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.

5 results :

SMCR8 适用: 人, 小鼠 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7095499
 
SMCR8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452051
 
SMCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6753676
 
SMCR8 适用: 人, 犬, 马, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2791916
 
SMCR8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602575
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunoprecipitation (IP)
  • 适用
    • Human
    • Dog
    • Horse
    • Mouse
    • Rabbit
    • Rat
  • 图像
  • 抗体来源
    • Rabbit
  • 克隆形成能力
    • Polyclonal
  • 抗原表位
    • AA 600-650
    • AA 841-890
    • AA 86-776
    • C-Term
  • 标记
    • 非结合性
  • 抗体亚型
    • IgG
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Aviva Systems Biology
    • Boster Bio

Aliases for SMCR8 抗体

Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8) 抗体
Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8) 抗体
Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8) 抗体
Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b) 抗体
2310076G09Rik 抗体
AI642055 抗体
D030073L15Rik 抗体
RGD1564621 抗体
smcr8 抗体
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