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SMC6 产品

(SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Categories

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).

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Featured SMC6 Categories

SMC6 抗体

High quality antibodies with extensive validation data.

SMC6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SMC6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (4)
Cat. No. ABIN566368
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7170874
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN872381
Quantity 100 μL
Datasheet Datasheet

Recommended SMC6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6221429
Quantity 96 tests
Datasheet Datasheet

Recommended SMC6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320665
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095550
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136902
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SMC6 Products

Murphy, Xu, Li, Nio, Reszka-Blanco, Li, Wu, Yu, Xiong, Su: "Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication." in: Cell reports, Vol. 16, Issue 11, pp. 2846-2854, (2017) (PubMed).

Niu, Livingston, Li, Beran, Daffis, Ramakrishnan, Burdette, Peiser, Salas, Ramos, Yu, Cheng, Strubin, Delaney Iv, Fletcher: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).

Gallego-Paez, Tanaka, Bando, Takahashi, Nozaki, Nakato, Shirahige, Hirota: "Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells." in: Molecular biology of the cell, Vol. 25, Issue 2, pp. 302-17, (2014) (PubMed).

Synonyms and alternative names related to SMC6

structural maintenance of chromosomes 6 (SMC6), structural maintenance of chromosomes 6 (smc6), structural maintenance of chromosomes 6 (Smc6), 2810489L22Rik, 3830418C19Rik, AA990493, AU018782, AW742439, hSMC6, mKIAA4103, SMC-6, SMC6L1, Smc6l1

Protein level used designations for SMC6

  • SMC6 structural maintenance of chromosomes 6-like 1
  • SMC protein 6
  • structural maintenance of chromosomes protein 6
  • mSMC6
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