(Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7))
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011].
Barilli, Rotoli, Visigalli, Bussolati, Gazzola, DallAsta: "Arginine transport in human monocytic leukemia THP-1 cells during macrophage differentiation." in: Journal of leukocyte biology, Vol. 90, Issue 2, pp. 293-303, (2011) (PubMed).
Aliases for SLC7A7 抗体
solute carrier family 7 member 7 (SLC7A7) 抗体 solute carrier family 7 member 7 (Slc7a7) 抗体 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (Slc7a7) 抗体 AI790233 抗体 LAT3 抗体 LPI 抗体 MOP-2 抗体 my+lat1 抗体 y+LAT-1 抗体 Y+LAT1 抗体 y+LAT1 抗体