(Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5))
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia\; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. [provided by RefSeq, Oct 2009].
Sunagawa, Shimizu-Okabe, Kim, Kobayashi, Kosaka, Yanagawa, Matsushita, Okabe, Takayama: "Distinct development of the glycinergic terminals in the ventral and dorsal horns of the mouse cervical spinal cord." in: Neuroscience, Vol. 343, pp. 459-471, (2016) (PubMed).
Aliases for SLC6A5 抗体
solute carrier family 6 member 5 (SLC6A5) 抗体 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Slc6a5) 抗体 solute carrier family 6 member 5 (Slc6a5) 抗体 GLYT-2 抗体 Glyt2 抗体 GLYT2 抗体 HKPX3 抗体 NET1 抗体 prestin 抗体 SLC6A5 抗体