(Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011].
Halwachs, Lakoma, Schäfer, Seibel, Honscha: "The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier." in: Molecular pharmacology, Vol. 80, Issue 4, pp. 621-9, (2011) (PubMed).
Marchi, Paoluzzi, Scotto, Seshan, Zain, Zinzani, OConnor: "Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 14, pp. 3648-58, (2010) (PubMed).
Aliases for SLC19A1 抗体
replication factor C subunit 1 (RFC1) 抗体 solute carrier family 19 member 1 (SLC19A1) 抗体 folate transporter 1 (LOC100226745) 抗体 solute carrier family 19 (folate transporter), member 1 (Slc19a1) 抗体 solute carrier family 19 member 1 (Slc19a1) 抗体 solute carrier family 19 (folate transporter), member 1 L homeolog (slc19a1.L) 抗体 A1 抗体 AI323572 抗体 CHMD 抗体 chmd 抗体 FOLT 抗体 folt 抗体 IFC1 抗体 ifc1 抗体 LOC100226745 抗体 MHCBFB 抗体 MTX1 抗体 PO-GA 抗体 RECC1 抗体 REFC 抗体 refc 抗体 RFC 抗体 RFC-1 抗体 RFC1 抗体 rfc1 抗体 RFC140 抗体 slc19a1 抗体 XRFC 抗体