(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7))
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).
Brown, Murtha, Rubinstein, Korah, Carling: "SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior." in: Cell communication and signaling : CCS, Vol. 16, Issue 1, pp. 27, (2019) (PubMed).
Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: "Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18083-93, (2007) (PubMed).
Aliases for SLC12A7 抗体
solute carrier family 12 (potassium/chloride transporters), member 7 (SLC12A7) 抗体 solute carrier family 12 member 7 (SLC12A7) 抗体 solute carrier family 12 member 7 (Slc12a7) 抗体 solute carrier family 12, member 7 (Slc12a7) 抗体 AA408796 抗体 D13Ertd261e 抗体 KCC4 抗体 Kcc4 抗体 Slc12a5 抗体 SLC12A7 抗体