SH3PXD2A 抗体
(SH3 and PX Domains 2A (SH3PXD2A))
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide (By similarity).
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Aliases for SH3PXD2A 抗体
SH3 and PX domains 2A (SH3PXD2A) 抗体SH3 and PX domains 2A (Sh3pxd2a) 抗体
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