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抗Human Aquaporin 4 抗体:
抗Mouse (Murine) Aquaporin 4 抗体:
抗Rat (Rattus) Aquaporin 4 抗体:
Human Polyclonal Aquaporin 4 Primary Antibody for IF (p), IHC (p) - ABIN671181
Duan, Hao, Fan, Wang, Liu, Hao, Xu, Liu, Zhang: The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injury. in The Journal of surgical research 2013
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Human Polyclonal Aquaporin 4 Primary Antibody for ICC, IF - ABIN4281307
Lopez-Rodriguez, Acaz-Fonseca, Viveros, Garcia-Segura: Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit. in PLoS ONE 2015
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Human Monoclonal Aquaporin 4 Primary Antibody for EIA, IHC (fro) - ABIN119571
Esposito, Imitola, Lu, De Filippis, Scuderi, Ganesh, Folkerth, Hecht, Shin, Iuvone, Chesnut, Steardo, Sheen: Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury. in Human molecular genetics 2008
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Human Monoclonal Aquaporin 4 Primary Antibody for EIA, IHC (fro) - ABIN119570
Bódis, Nagy, Németh, Mózsik: Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats. in Journal of physiology, Paris 2001
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Ordered disorder of the astrocytic dystrophin (显示 DMD 抗体)-associated protein complex in the norm and pathology.
the AQP4 could play a role in the regulation of water balance and ion transport in the sensory cells of zebrafish, bringing new data for the utilizing of this experimental model in the biology of sensory system.
These results suggest that AQP4 is damaged first and decrease of EAAT-2 (显示 SLC1A2 抗体) may follow in pathogenesis of cortical degeneration. This is the first demonstration of decrease of AQP4 and its association with EAAT-2 (显示 SLC1A2 抗体) decrease in AIDS brain, suggesting a role in the pathogenesis of HIV-associated neurocognitive disorders.
Report the value of spinal cord biopsy in the diagnosis of aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
identified that TMZ might have therapeutic potential for controlling proliferation, invasion of malignant glioma by inhibiting AQP4 expression through activation of p38 (显示 CRK 抗体) signal transduction pathway
The purpose of this study was to determine whether or not aquaporin-4 (AQP4) gene mutations are related to the pathogenesis of inflammatory demyelinating diseases in the central nervous system.
Comparative molecular dynamics study of neuromyelitis optica-immunoglobulin G binding to AQP4 extracellular domains has been presented.
Osmotic water permeabilities of aquaporins AQP4, AQP5 (显示 AQP5 抗体), and GlpF from near-equilibrium simulations have been presented.
A clear correlation between AQP4 expression and ADCmax values in grade I meningioma was identified.
Peritumoral brain edema in patients with meningiomas may depend on AQP4 expression grades and not on tumor grade, tumor volume, Ki-67 (显示 MKI67 抗体) expression, and cell count.
AQP4 antibodies were higher in neuromyelitis optica Chinese Han patients with circulating auto-antibodies.
Retinal nerve fiber layer may be better preserved in MOG-IgG versus AQP4-IgG optic neuritis.
AQP4-autoantibody serostatus correlated with poor visual outcome in neuromyelitis optica (Meta-analysis)
in vivo studies demonstrated that LPS (显示 TLR4 抗体)-induced activated microglia did not express AQP4, and in vitro that AQP4 deficiency inhibited astrocyte activation and reduced the release of proinflammatory cytokines from astrocytes.
The present data point to a salient glial contribution to CSD (显示 CSAD 抗体) and identify AQP4 as a new target for therapy.
Aquaporin-4 (AQP4) water channels in astrocytes regulate basal brain water content.
Apelin (显示 APLN 抗体)-13 protects blood brain barrier from disruption after cerebral ischemia both morphologically and functionally, which is highly associated with the increased levels of AQP4, possibly through the activation of ERK (显示 EPHB2 抗体) and PI3K/Akt (显示 AKT1 抗体) pathways.
Aquaporin-4 has two isoforms, M1 and M23, whose transcripts are driven by distinct promoters. A fragment located between exons 0 and 1 of the aquaporin-4 gene, which had been thought to be the promoter for M23, lacked enhancers functioning in astrocytes. When the astrocyte-specific enhancer (ASE (显示 ARSE 抗体)) of the M1 promoter is connected to the putative M23 core promoter, it also works in astrocytes.
In anhedonic mice, the expression of the water channel aquaporin 4 (AQP4), a factor in glymphatic pathway dysfunction, was down-regulated in cortex and hippocampus.
The results of this study that AQP4 and GLT1 do not have a strong physical interaction between them and are, instead, differentially regulated.
Study suggests that astaxanthin may exert neuroprotection following traumatic brain injury by ameliorating AQP4/NKCC1 (显示 SLC12A2 抗体)-mediated cerebral edema, and NKCC1 (显示 SLC12A2 抗体) inactivation inhibitions the upregulation of AQP4 after traumatic brain injury.
this study identified and fine mapped the major T-cell epitope of AQP4 and observed that in a transfer model, AQP4-specific T cells alone induced an encephalomyelitic syndrome, however, only in the additional presence of anti-AQP4 antibodies, central nervous system lesions are reminiscent of neuromyelitis optica
Study found that aquaporin-4 deficiency facilitated fear memory extinction and NMDA receptors-dependent long-term depression in the CA3 (显示 CA3 抗体)-CA1 (显示 CA1 抗体) hippocampal pathway.
AQP4 plays an important role in mediating brain edema in hypoxic-ischemic encephalopathy.
constitutive recycling of AQP2 (显示 AQP2 抗体) does not require phosphorylation at any C-terminal sites
In conclusion, HPO (显示 GFER 抗体) can decrease AQP4 expression in brain tissue of rabbits with cerebral hemorrhage to suppress the progression of brain edema and promote repairing of injured tissue.
AQP4 may play an important role in brain edema after severe scald (显示 RDH11 抗体).
In the guinea pig AQP4 is localised to enteric glial cells.
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, aquaporin 4
, aquaporin type4
, mercurial-insensitive water channel
, aquaporin 4.M23
, mercurial insensitive water channel
, water channel