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APPL2 抗体

(Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2))
The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome. [provided by RefSeq, Oct 2011].
APPL2 抗体  (AA 1-664) APPL2 抗体  (AA 1-664) APPL2 抗体 (AA 1-664) (ABIN527414)

APPL2 适用: 人 IF, WB 宿主: 小鼠 Polyclonal unconjugated

APPL2 抗体  (AA 174-273) APPL2 抗体  (AA 174-273) APPL2 抗体 (AA 174-273) (ABIN527415)

APPL2 适用: 人 IF, ELISA, WB 宿主: 小鼠 Monoclonal 1C10 unconjugated

APPL2 抗体  (AA 399-512) APPL2 抗体  (AA 399-512) APPL2 抗体 (AA 399-512) (ABIN7149505)

APPL2 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

APPL2 抗体 by 适用

Find APPL2 抗体 for a variety of species such as anti-Human APPL2, anti-Mouse APPL2, anti-Rat APPL2. The species listed below are among those available. Click on a link to go to the corresponding products.

APPL2 抗体 by 应用范围

Find APPL2 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

APPL2 抗体 by 抗体来源

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APPL2 抗体 by 抗原表位

Find APPL2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APPL2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal APPL2 抗体. Click on a link to go to the corresponding products.

APPL2 抗体 by 克隆

Find APPL2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

APPL2 抗体 by 标记

Find APPL2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APPL2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN527414
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (4)
Cat. No. ABIN527415
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7149505
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (1)
Cat. No. ABIN7265444
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7149508
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7149507
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7149506
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
Cat. No. ABIN7111302
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1539001
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1807972
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2568583
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application IF, WB
Validations
Cat. No. ABIN2568582
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2568584
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN1960799
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN1963174
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our APPL2 抗体

Gaspar, Muñoz, Kuga, Nakandakari, Crisol, Lenhare, Breda, Botezelli, SantAna, da Silva, Cintra, de Moura, Ropelle, Pauli: "Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice." in: The European journal of neuroscience, (2019) (PubMed).

Canciglieri, Kuga, Muñoz, Gaspar, da Rocha, Breda, Anaruma, Minuzzi, da Silva, Cintra, de Moura, Ropelle, Pauli: "The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle." in: Life sciences, Vol. 210, pp. 209-213, (2018) (PubMed).

Gaspar, Muñoz, Formigari, Kuga, Nakandakari, Botezelli, da Silva, Cintra, de Moura, Ropelle, Pauli: "Acute physical exercise increases the adaptor protein APPL1 in the hypothalamus of obese mice." in: Cytokine, Vol. 110, pp. 87-93, (2018) (PubMed).

Cleasby, Lau, Polkinghorne, Patel, Leslie, Turner, Cooney, Xu, Kraegen: "The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway." in: The Journal of endocrinology, Vol. 210, Issue 1, pp. 81-92, (2011) (PubMed).

Aliases for APPL2 抗体

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (Appl2) 抗体
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) 抗体
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 L homeolog (appl2.L) 抗体
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) 抗体
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (appl2) 抗体
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) 抗体
APPL2 抗体
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dip13b 抗体
DIP13B 抗体
MGC84621 抗体
RGD1563028 抗体
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