ARAP2 抗体
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008].
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Latest Publications for our ARAP2 抗体
: "ARAP1: a point of convergence for Arf and Rho signaling." in: Molecular cell, Vol. 9, Issue 1, pp. 109-19, (2002) (PubMed).
Aliases for ARAP2 抗体
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (ARAP2) 抗体ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (Arap2) 抗体
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (LOC100567363) 抗体
ARAP2 抗体
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