The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008].
Guillemot, Thouënnon, Guérin, Vallet-Erdtmann, Ravni, Montéro-Hadjadje, Lefebvre, Klein, Muresan, Seidah, Anouar, Yon: "Differential expression and processing of secretogranin II in relation to the status of pheochromocytoma: implications for the production of the tumoral marker EM66." in: Journal of molecular endocrinology, Vol. 48, Issue 2, pp. 115-27, (2012) (PubMed).
Aliases for SCG2 抗体
secretogranin II L homeolog (scg2.L) 抗体 secretogranin II (chromogranin C), b (scg2b) 抗体 secretogranin II (scg2) 抗体 secretogranin II (SCG2) 抗体 Secretogranin-2 (scg2) 抗体 secretogranin II (Scg2) 抗体 Chcg 抗体 CHGC 抗体 Chgc 抗体 DKFZp459O193 抗体 EM66 抗体 LOC397939 抗体 MGC84703 抗体 MGC145924 抗体 scg2 抗体 SCG2 抗体 SCGG2 抗体 SgII 抗体 SN 抗体 wu:fj34e01 抗体 zgc:153925 抗体