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SARS-CoV-2 Spike S1 蛋白

(SARS-CoV-2 Spike S1)
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.

100 results

宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 85 % SDS, AcA Active
产品编号 ABIN7677285
 
宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
产品编号 ABIN7677289
 
宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % by SDS - PAGE SDS, AcA Active
产品编号 ABIN7677315
 
宿主: SARS Coronavirus (SARS-CoV) 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
产品编号 ABIN7677280
 
宿主: SARS Coronavirus (SARS-CoV) 宿主: HEK-293 Cells Recombinant > 95 % by SDS - PAGE SDS, AcA Active
产品编号 ABIN7677306
 
宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 85 % ELISA Active
产品编号 ABIN7669709
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 90 % ELISA Active
产品编号 ABIN7669708
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 90 % ELISA Active
产品编号 ABIN7669705
20 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7825143
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 1 reference
产品编号 ABIN7013339
200 μg (More quantities available)
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron 宿主: HEK-293 Cells Recombinant > 95% as determined by SDS-PAGE. SDS
产品编号 ABIN7041437
100 μg (More quantities available)
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron 宿主: HEK-293 Cells Recombinant 95,00 %
产品编号 ABIN7316955
100 μg (More quantities available)
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron 宿主: HEK-293 Cells Recombinant 95,00 %
产品编号 ABIN7316956
100 μg (More quantities available)
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013124
100 μg (More quantities available)
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7121366
100 μg (More quantities available)
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌(E. Coli) Recombinant >95 %
产品编号 ABIN6952323
100 μg (More quantities available)
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC ELISA, WB
产品编号 ABIN6952973
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC ELISA, WB
产品编号 ABIN6952972
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC ELISA, WB
产品编号 ABIN6952974
100 μg
发货至: 中国
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宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 人细胞 Recombinant >95% as determined by SDS-PAGE. ELISA, WB
产品编号 ABIN6952980
100 μg
发货至: 中国
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  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Activity Assay (AcA)
    • Affinity Measurement (AM)
    • Functional Studies (Func)
    • Immunoassay (IA)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Lateral Flow (LF)
    • Control (Ct)
    • Enzyme Immunoassay (EIA)
    • Immunogen (Imm)
    • Positive Control (PC)
  • 适用
    • SARS Coronavirus-2 (SARS-CoV-2)
    • SARS Coronavirus (SARS-CoV)
    • SARS CoV-2 Beta
    • SARS CoV-2 Omicron
    • SARS CoV-2 Delta
    • Coronavirus (CoV)
    • SARS CoV-2 Alpha
  • 论文引用
  • 图像
  • 仅无防腐剂
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Escherichia coli (E. coli)
    • Insect Cells
    • CHO Cells
    • Human Cells
    • Tobacco (Nicotiana benthamiana)
  • 抗原表位
    • RBD
    • AA 14-683
    • AA 16-685
    • AA 319-541
    • D614G
    • N-Term
    • AA 14-667
    • AA 16-6
    • B.1.1.529 - Omicron
    • B.1.351 - beta
    • AA 1-674
    • AA 13-303
    • B.1.617.2 - delta
    • N501Y
    • Receptor Binding Domain
    • AA 14-6
    • AA 306-515
    • BA.4 - Omicron
    • BA.5 - Omicron
    • Extracellular Domain
    • AA 1-305
    • AA 1-681
    • AA 1-685
    • AA 13-6
    • AA 14-685
    • AA 16-305
    • AA 315-535
    • AA 330-530
    • AA 334-527
    • Asp614Gly
    • B.1.1.7 - alpha
    • B.1.640.2
    • BA.2 - Omicron
    • BA.2.12.1 - Omicron
    • BA.2.75 - Omicron
    • BA.5.2 - Omicron
    • C-Term
    • C.37 - Lambda
    • E484K
    • G476S
    • K417N
    • NTD
    • P.1 - gamma
    • P.1.1 - Gamma
    • P.1.2 - Gamma
    • Subunit S1
    • V367F
    • V483A
    • W436R
  • 标记
    • His tag
    • Fc Tag
    • mFc Tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag
    • Biotin,His-Avi Tag
    • hFc-Avi Tag
    • hFc-Avi Tag,Biotin
    • 非结合性
    • Biotin
    • Fc-Avi Tag
    • Fc-His Tag
    • GST tag,His tag
    • His tag,Biotin
    • His tag,Fc Tag
    • His tag,SEKDEL Tag
    • His-Avi Tag,Biotin
    • His-DYKDDDDK Tag
    • hFc Tag
    • sFc-Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • RayBiotech

Latest Publications for our SARS-CoV-2 Spike S1 蛋白

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Fan, Parr, Kang, Gupta: "Point-of-care (POC) SARS-CoV-2 antigen detection using functionalized aerosol jet-printed organic electrochemical transistors (OECTs)." in: Nanoscale, Vol. 15, Issue 11, pp. 5476-5485, (2023) (PubMed).

Kaneko, Satta, Komuro, Muthukrishnan, Kakarla, Guo, An, Elahi, Kornblum, Liebeskind, Hsiai, Hinman: "Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection." in: Stroke, Vol. 52, Issue 1, pp. 260-270, (2021) (PubMed).

Sasisekharan, Pentakota, Jayaraman, Tharakaraman, Wogan, Narayanasami: "Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 5, (2021) (PubMed).

Dogan, Kozhaya, Placek, Gunter, Yigit, Hardy, Plassmeyer, Coatney, Lillard, Bukhari, Kleinberg, Hayes, Arditi, Klapper, Merin, Liang, Gupta, Alpan, Unutmaz: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).

Narang, James, Balmer, Wilson: "Protein Footprinting, Conformational Dynamics, and Core Interface-Adjacent Neutralization "Hotspots" in the SARS-CoV-2 Spike Protein Receptor Binding Domain/Human ACE2 Interaction." in: Journal of the American Society for Mass Spectrometry, (2021) (PubMed).

Fiedler, Piziorska, Denninger, Morgunov, Ilsley, Malik, Schneider, Devenish, Meisl, Kosmoliaptsis, Aguzzi, Fiegler, Knowles: "Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum." in: ACS infectious diseases, (2021) (PubMed).

Lucas, Klein, Sundaram, Liu, Wong, Silva, Mao, Oh, Mohanty, Huang, Tokuyama, Lu, Venkataraman, Park, Israelow, Vogels, Muenker, Chang, Casanovas-Massana, Moore, Zell, Fournier, Wyllie, Campbell, Lee et al.: "Delayed production of neutralizing antibodies correlates with fatal COVID-19. ..." in: Nature medicine, (2021) (PubMed).

Song, Bartley, Chow, Ngo, Jiang, Zamecnik, Dandekar, Loudermilk, Dai, Liu, Sunshine, Liu, Wu, Hawes, Alvarenga, Huynh, McAlpine, Rahman, Geng, Chiarella, Goldman-Israelow, Vogels, Grubaugh et al.: "Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. ..." in: Cell reports. Medicine, pp. 100288, (2021) (PubMed).

Guo, Huang, Zhang, Yao, Zhou, Shen, Shen, Li, Li, Zhang, Chen, Chen, Wu, Fu, Zeng, Feng, Pi, Wang, Zhou, Lu, Li, Fang, Lu, Hu, Wang, Zhang, Gao, Adrian, Wang, Yu, Peng, Gabibov, Min, Wang, Huang et al.: "A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. ..." in: Nature communications, Vol. 12, Issue 1, pp. 2623, (2021) (PubMed).

Aliases for SARS-CoV-2 Spike S1 蛋白

Surface Glycoprotein (S) 蛋白
E2 蛋白
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