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Sacsin 抗体

(Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that 'the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins' (Parfitt et al., PubMed: 19208651). [provided by RefSeq, Apr 2012].
Sacsin 抗体  (AA 983-1150) Sacsin 抗体  (AA 983-1150) Sacsin 抗体 (AA 983-1150) (ABIN7168566)

SACS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

Sacsin 抗体  (AA 3709-3909) Sacsin 抗体  (AA 3709-3909) Sacsin 抗体 (AA 3709-3909) (ABIN5693301)

SACS 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated

Sacsin 抗体 Sacsin 抗体 Sacsin 抗体 (ABIN5708501)

SACS 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Sacsin 抗体 by 适用

Find Sacsin 抗体 for a variety of species such as anti-Human Sacsin, anti-Mouse Sacsin, anti-Rat Sacsin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Sacsin 抗体 validated for a specific application such as ELISA, IHC, WB, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Sacsin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Sacsin 抗体 by 克隆形成能力

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Sacsin 抗体 by 标记

Find Sacsin 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Sacsin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7168566
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN5693301
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5708501
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168569
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7168568
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168567
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p)
Validations
Cat. No. ABIN6390208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
Cat. No. ABIN7119378
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IP
Validations
Cat. No. ABIN7450705
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN6113843
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
Cat. No. ABIN1982323
Quantity 50 μg
Datasheet Datasheet

Aliases for Sacsin 抗体

sacsin (Sacs) 抗体
sacsin molecular chaperone (SACS) 抗体
A230052M14 抗体
ARSACS 抗体
DNAJC29 抗体
E130115J16Rik 抗体
mKIAA0730 抗体
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