Sacsin 抗体 (AA 3709-3909) (APC)
Our Local Distributor
北京 101111
Quick Overview for Sacsin 抗体 (AA 3709-3909) (APC) (ABIN8041338)
抗原
See all Sacsin (SACS) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 3709-3909
-
原理
- Anti-Sacsin Antibody APC Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human Sacsin recombinant protein (Position: E3709-L3909).
-
亚型
- IgG
-
-
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 983-1150) antibody
SACS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 3709-3909) antibodySACS 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 175-225) antibodySACS 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Sacsin (SACS) (Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
-
别名
- SACS
-
背景
-
Background: Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. This modular protein is essential for normal mitochondrial network organization. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticityand peripheral neuropathy.
Gene Full Name: sacsin molecular chaperone
-
基因ID
- 26278
-
UniProt
- Q9NZJ4
抗原
-
