Retinal Pigment Epithelium-Specific Protein 65kDa 产品
(Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
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This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008].
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Featured Retinal Pigment Epithelium-Specific Protein 65kDa Categories
Retinal Pigment Epithelium-Specific Protein 65kDa 抗体
High quality antibodies with extensive validation data.
Retinal Pigment Epithelium-Specific Protein 65kDa ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Retinal Pigment Epithelium-Specific Protein 65kDa 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Retinal Pigment Epithelium-Specific Protein 65kDa 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7167824
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow
Application
WB, IHC, ICC, IHC (fro)
Validations
- (5)
- (2)
Cat. No.
ABIN534120
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6147090
Quantity
100 μL
Datasheet
Datasheet
Recommended Retinal Pigment Epithelium-Specific Protein 65kDa ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1155364
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Validations
Cat. No.
ABIN1155365
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1155366
Quantity
96 tests
Datasheet
Datasheet
Recommended Retinal Pigment Epithelium-Specific Protein 65kDa 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3095121
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3136848
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422823
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Retinal Pigment Epithelium-Specific Protein 65kDa Products
: "Advantages of nanofibrous membranes for culturing of primary RPE cells compared to commercial scaffolds." in: Acta ophthalmologica, (2021) (PubMed).: "The role of Wnt/β-catenin signaling in the restoration of induced pluripotent stem cell-derived retinal pigment epithelium after laser photocoagulation." in: Lasers in medical science, Vol. 34, Issue 3, pp. 571-581, (2019) (PubMed).
: "High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD." in: Experimental eye research, Vol. 185, pp. 107641, (2019) (PubMed).
: "Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina." in: The Journal of biological chemistry, Vol. 293, Issue 37, pp. 14507-14519, (2019) (PubMed).
: "Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments." in: Stem cells translational medicine, Vol. 8, Issue 8, pp. 797-809, (2019) (PubMed).
: "Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs." in: Cytometry. Part A : the journal of the International Society for Analytical Cytology, (2019) (PubMed).
: "Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells." in: Cell death & disease, Vol. 8, Issue 10, pp. e3115, (2018) (PubMed).
: "An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy." in: Investigative ophthalmology & visual science, Vol. 59, Issue 4, pp. AMD143-AMD151, (2018) (PubMed).
: "Organoid technology for retinal repair." in: Developmental biology, Vol. 433, Issue 2, pp. 132-143, (2018) (PubMed).
: "Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. 9014-9019, (2018) (PubMed).
Synonyms and alternative names related to Retinal Pigment Epithelium-Specific Protein 65kDa
RPE65, retinoid isomerohydrolase (RPE65), retinal pigment epithelium 65 (Rpe65), neither inactivation nor afterpotential B (ninaB), RPE65, retinoid isomerohydrolase (Rpe65), retinal pigment epithelium-specific protein 65kDa S homeolog (rpe65.S), retinal pigment epithelium-specific protein 65kDa L homeolog (rpe65.L), RPE65 homolog (rpe65), retinal pigment epithelium-specific protein 65kDa (rpe65), retinal pigment epithelium-specific protein 65c (rpe65c), retinal pigment epithelium-specific protein 65b (rpe65b), retinal pigment epithelium-specific protein 65a (rpe65a), 13cIMH, 65kDa, A930029L06Rik, anon-WO0148162.1, anon-WO0148163.1, beta-diox, CG9347, DmelCG9347, DRPE65, LCA2, MGC52887, MGC85437, MGC154296, Mord1, mRPE65, rd12, RP20, RPE56a, RPE56b, RPE56c, RPE65, rpe65, rpepa, rpepb, si:ch211-198n5.5, si:ch211-198n5.12, sRPE65, wu:fc74c09, zgc:73213, zgc:110538Protein level used designations for Retinal Pigment Epithelium-Specific Protein 65kDa
- RBP-binding membrane protein
- all-trans-retinyl-palmitate hydrolase
- p63
- retinal pigment epithelium-specific 65 kDa protein
- retinitis pigmentosa 20 (autosomal recessive)
- retinoid isomerohydrolase
- retinol isomerase
- modifier of retinal degeneration 1
- retinal pigment epithelium, 65 kDa
- neither inactivation nor afterpotential B
- CG9347-PA
- ninaB-PA
- beta-carotene dioxygenase
- retinal pigment epithelium 65-like
- retinal pigment epithelium-specific protein (65kD)
- retinal pigment epithelium-specific protein 65kDa
- retinal pigment epithelium abundant protein RPE65
- rpe65 gene for retinal pigment epithelium-specific protein
- RPE65 homolog
- retinoid isomerohydrolase-like
- All-trans-retinyl ester 13-cis isomerohydrolase C
- All-trans-retinylester 11-cis isomerohydrolase C
- Retinal pigment epithelium-specific 65 kDa protein homolog C
- retinal Mueller cells isomerohydrolase
- 13cIMH
- Retinal pigment epithelium-specific 65 kDa protein homolog B
- all-trans-retinyl ester 13-cis isomerohydrolase
- retinal pigment epithelium 65b
- retinal pigment epithelium-specific 65 kDa protein homolog B
- retinal pigment epithelium-specific protein b
- All-trans-retinylester 11-cis isomerohydrolase A
- Retinal pigment epithelium-specific 65 kDa protein homolog A
- all-trans-retinylester 11-cis isomerohydrolase A
- retinal pigment epithelium 65a
- retinal pigment epithelium-specific 65 kDa protein homolog A
- retinal pigment epithelium-specific protein a
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