The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010].
Wang, Sang, Ren, Liu, Liu, Zhang, Wang, Wang, Orian, Yang, Yi: "SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation." in: Protein & cell, (2015) (PubMed).
Aliases for RNF4 抗体
ring finger protein 4 (RNF4) 抗体 ring finger protein 4 (Rnf4) 抗体 AU018689 抗体 Gtrgeo8 抗体 SLX5 抗体 SNURF 抗体