RNF4 抗体
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- 抗原 See all RNF4 抗体
- RNF4 (Ring Finger Protein 4 (RNF4))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF4 antibody is un-conjugated
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应用范围
- ELISA, Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- ring finger protein 4
- 亚型
- IgG
- Top Product
- Discover our top product RNF4 Primary Antibody
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anti-Ring Finger Protein 4 (RNF4) antibody
RNF4 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 1-103) antibodyRNF4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 471-724) antibodyRNF4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 107-190) antibodyRNF4 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 95-123) antibodyRNF4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 1-190) antibodyRNF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 4 (RNF4) (AA 94-123), (C-Term) antibodyRNF4 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IP: 1:200-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- RNF4 (Ring Finger Protein 4 (RNF4))
- 别名
- RNF4 (RNF4 产品)
- 别名
- SLX5 antibody, SNURF antibody, AU018689 antibody, Gtrgeo8 antibody, ring finger protein 4 antibody, RNF4 antibody, Rnf4 antibody
- 背景
- Synonyms:SNURF Background:E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'-and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation. Regulates the degradation of several proteins including PML and the transcriptional activator PEA3. Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation. Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1. Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation.
- 基因ID
- 6047
- UniProt
- P78317
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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