RNF111 抗体
(Ring Finger Protein 111 (RNF111))
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
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50 results
RNF111
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC, IF, ICC, FACS
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our RNF111 抗体
: "The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma." in: Oncogene, Vol. 35, Issue 27, pp. 3514-23, (2016) (PubMed).: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).
: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." in: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).
: "Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control." in: Molecular and cellular biology, Vol. 34, Issue 16, pp. 2981-95, (2014) (PubMed).
: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).
: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).
: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).
: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).
: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).
: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).
Aliases for RNF111 抗体
ring finger protein 111 (RNF111) 抗体ring finger 111 (Rnf111) 抗体
ring finger protein 111 (Rnf111) 抗体
ring finger protein 111 (rnf111-b) 抗体
ring finger protein 111 (rnf111) 抗体
ARK 抗体
ark 抗体
Arkadia 抗体
MGC81253 抗体
MGC146379 抗体
RNF111 抗体
rnf111 抗体
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