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RNF111 抗体 (AA 901-950)

The 兔 多克隆 anti-RNF111 antibody (ABIN1451235) specifically detects RNF111 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1451235
发货至: 中国
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Quick Overview for RNF111 抗体 (AA 901-950) (ABIN1451235)

抗原

See all RNF111 抗体
RNF111 (Ring Finger Protein 111 (RNF111))

适用

  • 62
  • 30
  • 21
人, 小鼠

宿主

  • 58
  • 4
兔

克隆类型

  • 60
  • 2
多克隆

标记

  • 20
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF111 antibody is un-conjugated

应用范围

  • 33
  • 26
  • 15
  • 14
  • 13
  • 13
  • 12
  • 11
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 13
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 901-950

    原理

    Arkadia Antibody

    特异性

    Arkadia Polyclonal Antibody detects endogenous levels of Arkadia protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human RNF111. AA range:901-950

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RNF111 (Ring Finger Protein 111 (RNF111))

    别名

    RNF111

    背景

    Synonyms: RNF111, E3 ubiquitin-protein ligase Arkadia, RING finger protein 111

    Background: ring finger protein 111(RNF111) Homo sapiens The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],

    Gene Name: RNF111

    Protein Name: E3 ubiquitin-protein ligase Arkadia

    分子量

    108 kDa

    基因ID

    54778

    OMIM

    605840

    UniProt

    Q6ZNA4
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