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RNF111 抗体

The 兔 多克隆 anti-RNF111 antibody (ABIN7246457) specifically detects RNF111 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7246457
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RNF111 抗体 (ABIN7246457)

抗原

See all RNF111 抗体
RNF111 (Ring Finger Protein 111 (RNF111))

适用

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宿主

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克隆类型

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多克隆

标记

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This RNF111 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human RNF111

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:300, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.84 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RNF111 (Ring Finger Protein 111 (RNF111))

    别名

    RNF111

    背景

    The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

    UniProt

    Q6ZNA4
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