RBPJ 抗体
(Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011].
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Latest Publications for our RBPJ 抗体
: "RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13794-807, (2010) (PubMed).
: "A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 ..." in: Journal of virology, Vol. 79, Issue 14, pp. 8784-92, (2005) (PubMed).
: "A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 ..." in: Journal of virology, Vol. 79, Issue 14, pp. 8784-92, (2005) (PubMed).
Aliases for RBPJ 抗体
recombination signal binding protein for immunoglobulin kappa J region (RBPJ) 抗体recombination signal binding protein for immunoglobulin kappa J region (Rbpj) 抗体
recombination signal binding protein for immunoglobulin kappa J region S homeolog (rbpj.S) 抗体
recombination signal binding protein for immunoglobulin kappa J region a (rbpja) 抗体
recombination signal binding protein for immunoglobulin kappa J region b (rbpjb) 抗体
AI843960 抗体
AOS3 抗体
CBF1 抗体
csl 抗体
IGKJRB 抗体
Igkjrb 抗体
IGKJRB1 抗体
Igkrsbp 抗体
ik:tdsubc_1e8 抗体
KBF2 抗体
RBP-J 抗体
RBP-J kappa 抗体
rbpj 抗体
RBPJK 抗体
RBPjk 抗体
RBPSUH 抗体
Rbpsuh 抗体
rbpsuh 抗体
Su(H) 抗体
Su(H)1 抗体
Su(H)2 抗体
Su(h)A 抗体
su(h)B 抗体
SUH 抗体
XSu(H) 抗体
xsu(h)1 抗体
xx:tdsubc_1e8 抗体
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