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RASGRP4 抗体

(RAS Guanyl Releasing Protein 4 (RASGRP4))
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].

12 results :

RASGRP4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F3 unconjugated
Pubmed 1 reference
产品编号 ABIN566740
 
RASGRP4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855910
 
RASGRP4 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN530350
 
RASGRP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6747687
 
RASGRP4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN7510571
 
RASGRP4 适用: 人 WB, IHC (p), IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1833115
 
RASGRP4 适用: 人, 小鼠, 大鼠 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7095945
 
RASGRP4 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789029
 
RASGRP4 适用: 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN347761
 
RASGRP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1885956
 
RASGRP4 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1F3 unconjugated
产品编号 ABIN2348619
 
RASGRP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2348620
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Proximity Ligation Assay (PLA)
  • 适用
    • Human
    • Mouse
    • Pig
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1F3
  • 抗原表位
    • AA 1-673
    • N-Term
    • AA 108-170
    • AA 108-200
    • AA 149-198
    • AA 574-673
    • AA 574-674
  • 标记
    • 非结合性
  • 抗体亚型
    • IgG
    • IgG2a
    • IgG2a kappa
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • USBio
    • Aviva Systems Biology
    • Covalab
    • Signalway

Latest Publications for our RASGRP4 抗体

Shalom-Feuerstein, Levy, Makovski, Raz, Kloog: "Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras." in: Biochimica et biophysica acta, Vol. 1783, Issue 6, pp. 985-93, (2008) (PubMed).

Reuther, Lambert, Rebhun, Caligiuri, Quilliam, Der: "RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia." in: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30508-14, (2002) (PubMed).

Aliases for RASGRP4 抗体

RAS guanyl releasing protein 4 (RASGRP4) 抗体
RAS guanyl releasing protein 4 (rasgrp4) 抗体
RAS guanyl releasing protein 4 (Rasgrp4) 抗体
RASGRP4 抗体
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