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RASGRP4 抗体 (AA 108-170)

RASGRP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1885956
发货至: 中国
  • 抗原 See all RASGRP4 抗体
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 108-170
    适用
    • 10
    • 2
    • 1
    • 1
    宿主
    • 8
    • 3
    克隆类型
    • 9
    • 2
    多克隆
    标记
    • 11
    This RASGRP4 antibody is un-conjugated
    应用范围
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Synthetic peptide contain a sequence corresponding to a region within amino acids 108 and 170 of Human RASGRP4
    Top Product
    Discover our top product RASGRP4 Primary Antibody
  • 应用备注
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    Biohazard Informations: This product contains thimerosal which is hazardous.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    别名
    RASGRP4 (RASGRP4 产品)
    别名
    RASGRP4 antibody, RAS guanyl releasing protein 4 antibody, RASGRP4 antibody, rasgrp4 antibody, Rasgrp4 antibody
    背景
    The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors.It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands.This protein was shown to activate H-Ras in a cation-dependent manner in vitro.Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways.Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
    分子量
    75 kDa
    基因ID
    115727
    NCBI登录号
    NM_170604, NP_733749
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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