PTPN1 抗体
(Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PTPN1 抗体 (AA 1-100) (PE) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (Cy5) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (Cy5.5) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (Biotin) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (Cy7) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (Cy3) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-100) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 281-435) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-321) | 人 | 兔 Polyclonal |
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| PTPN1 抗体 (pSer50) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-321) (HRP) | 人, 小鼠 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 221-249) (Biotin) | 小鼠 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 385-435) | 人, 马 | 兔 Polyclonal |
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| PTPN1 抗体 (AA 1-321) (APC) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 281-435
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-321
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer50
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-321
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 221-249
Primary Antibody
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 马
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 385-435
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-321
Latest Publications for our PTPN1 抗体
: "Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models." in: Oncology reports, Vol. 34, Issue 4, pp. 2047-53, (2016) (PubMed).
: "Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet." in: Journal of hepatology, Vol. 63, Issue 3, pp. 713-21, (2016) (PubMed).
: "Memory and PTPIP51--a new protein in hippocampus and cerebellum." in: Molecular and cellular neurosciences, Vol. 64, pp. 61-73, (2015) (PubMed).
: "Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression." in: Biomolecules, Vol. 2, Issue 1, pp. 122-42, (2014) (PubMed).
: "The known interactome of PTPIP51 in HaCaT cells - inhibition of kinases and receptors." in: The international journal of biochemistry & cell biology, (2014) (PubMed).
: "IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 11, pp. 1969-79, (2013) (PubMed).
: "PTPIP51 in protein interactions: regulation and in situ interacting partners." in: Cell biochemistry and biophysics, Vol. 63, Issue 3, pp. 211-22, (2012) (PubMed).
: "Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts." in: Arthritis and rheumatism, Vol. 64, Issue 6, pp. 1978-89, (2012) (PubMed).
: "PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia." in: Leukemia research, Vol. 35, Issue 10, pp. 1367-75, (2011) (PubMed).
: "In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis." in: Trends in cell biology, Vol. 20, Issue 11, pp. 672-9, (2010) (PubMed).
: "Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet." in: Journal of hepatology, Vol. 63, Issue 3, pp. 713-21, (2016) (PubMed).
: "Memory and PTPIP51--a new protein in hippocampus and cerebellum." in: Molecular and cellular neurosciences, Vol. 64, pp. 61-73, (2015) (PubMed).
: "Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression." in: Biomolecules, Vol. 2, Issue 1, pp. 122-42, (2014) (PubMed).
: "The known interactome of PTPIP51 in HaCaT cells - inhibition of kinases and receptors." in: The international journal of biochemistry & cell biology, (2014) (PubMed).
: "IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 11, pp. 1969-79, (2013) (PubMed).
: "PTPIP51 in protein interactions: regulation and in situ interacting partners." in: Cell biochemistry and biophysics, Vol. 63, Issue 3, pp. 211-22, (2012) (PubMed).
: "Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts." in: Arthritis and rheumatism, Vol. 64, Issue 6, pp. 1978-89, (2012) (PubMed).
: "PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia." in: Leukemia research, Vol. 35, Issue 10, pp. 1367-75, (2011) (PubMed).
: "In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis." in: Trends in cell biology, Vol. 20, Issue 11, pp. 672-9, (2010) (PubMed).
Aliases for PTPN1 抗体
protein tyrosine phosphatase, non-receptor type 1 (PTPN1) 抗体protein tyrosine phosphatase, non-receptor type 1 (Ptpn1) 抗体
protein tyrosine phosphatase, non-receptor type 1 (ptpn1) 抗体
protein tyrosine phosphatase, non-receptor type 1 L homeolog (ptpn1.L) 抗体
CPTP1 抗体
Ptp 抗体
PTP-1B 抗体
PTP-HA2 抗体
PTP1B 抗体
ptp1b 抗体
PTPN1 抗体
wu:fk54h03 抗体
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