PTK6 产品
(PTK6 Protein tyrosine Kinase 6 (PTK6))
Categories
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
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Featured PTK6 Categories
PTK6 抗体
High quality antibodies with extensive validation data.
PTK6 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PTK6 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTK6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
- (3)
Cat. No.
ABIN519483
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7263521
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6146427
Quantity
100 μL
Datasheet
Datasheet
Recommended PTK6 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958992
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5519121
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380961
Quantity
96 tests
Datasheet
Datasheet
Recommended PTK6 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5569664
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316783
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316782
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our PTK6 Products
: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).: "The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling." in: Marine drugs, Vol. 12, Issue 4, pp. 2282-304, (2014) (PubMed).
: "Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors." in: European journal of medicinal chemistry, Vol. 73, pp. 310-24, (2014) (PubMed).
: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).
: "Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models." in: PLoS ONE, Vol. 9, Issue 5, pp. e97622, (2014) (PubMed).
: "Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling." in: Organic & biomolecular chemistry, Vol. 12, Issue 28, pp. 5295-303, (2014) (PubMed).
: "Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo." in: Molecular oncology, Vol. 9, Issue 1, pp. 282-94, (2014) (PubMed).
: "Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma." in: Journal of translational medicine, Vol. 11, pp. 59, (2013) (PubMed).
: "A chemical and phosphoproteomic characterization of dasatinib action in lung cancer." in: Nature chemical biology, Vol. 6, Issue 4, pp. 291-9, (2010) (PubMed).
: "Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells." in: Oncogene, Vol. 22, Issue 27, pp. 4212-20, (2003) (PubMed).
Synonyms and alternative names related to PTK6
protein tyrosine kinase 6 (PTK6), PTK6 protein tyrosine kinase 6 (Ptk6), protein tyrosine kinase 6 (Ptk6), PTK6 protein tyrosine kinase 6b (ptk6b), BRK, Sik, tks, Tksk, zgc:153964Protein level used designations for PTK6
- PTK6 protein tyrosine kinase 6
- breast tumor kinase
- protein-tyrosine kinase 6
- protein-tyrosine kinase BRK
- tyrosine-protein kinase BRK
- protein tyrosine kinase 6
- src-related intestinal kinase
- tyrosine kinase identified from skin
- protein-tyrosine kinase 6-like
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