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PTF1A 产品

(Pancreas Specific Transcription Factor, 1a (PTF1A))
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008].

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Featured PTF1A Categories

PTF1A 抗体

High quality antibodies with extensive validation data.

PTF1A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PTF1A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTF1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7435103
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN531479
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN190768
Quantity 100 μg
Datasheet Datasheet

Recommended PTF1A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6574309
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511527
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1056871
Quantity 96 tests
Datasheet Datasheet

Recommended PTF1A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094805
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3137370
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403453
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PTF1A Products

Gorki, Hoenicka, Rupp, Müller-Eising, Deininger, Kunert, Liebold: "Similarity of coagulation and inflammation despite different surgical revascularization strategies - a prospective randomized trial." in: Perfusion, (2016) (PubMed).

Holmstrom, Deering, Swift, Poelwijk, Mangelsdorf, Kliewer, MacDonald: "LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function." in: Genes & development, Vol. 25, Issue 16, pp. 1674-9, (2011) (PubMed).

Bernardo, Cho, Mason, Docherty, Pedersen, Vallier, Docherty: "Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 2, pp. 341-51, (2009) (PubMed).

Yamada, Terao, Terashima, Fujiyama, Kawaguchi, Nabeshima, Hoshino: "Origin of climbing fiber neurons and their developmental dependence on Ptf1a." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 41, pp. 10924-34, (2007) (PubMed).

Pascual, Abasolo, Mingorance-Le Meur, Martínez, Del Rio, Wright, Real, Soriano: "Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5193-8, (2007) (PubMed).

Zecchin, Mavropoulos, Devos, Filippi, Tiso, Meyer, Peers, Bortolussi, Argenton: "Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates." in: Developmental biology, Vol. 268, Issue 1, pp. 174-84, (2004) (PubMed).

Synonyms and alternative names related to PTF1A

pancreas specific transcription factor, 1a (PTF1A), pancreas specific transcription factor, 1a (ptf1a), pancreas specific transcription factor, 1a (Ptf1a), bHLHa29, PTF1, PTF1-p48, PTF1A, Ptf1a/p48, PTF1p48, si:zc142h2.2, XPtf1a, zgc:112216

Protein level used designations for PTF1A

  • pancreas specific transcription factor, 1a
  • Ptfa
  • bHLH transcription factor p48
  • pancreas transcription factor 1 subunit alpha
  • pancreas-specific transcription factor 1a
  • Pancreas-specific transcription factor 1a
  • transcription factor Ptf1a/p48
  • class A basic helix-loop-helix protein 29
  • class II bHLH protein PTF1A
  • exocrine pancreas-specific transcription factor p48
  • p48 DNA-binding subunit of transcription factor PTF1
  • pancreas transcription factor1 p48 subunit
  • PTF1-p48
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