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PTGR1 产品

(Prostaglandin Reductase 1 (PTGR1))
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009].

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Featured PTGR1 Categories

PTGR1 抗体

High quality antibodies with extensive validation data.

PTGR1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PTGR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTGR1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN564974
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7164866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6257814
Quantity 100 μL
Datasheet Datasheet

Recommended PTGR1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958872
Quantity 96 tests
Datasheet Datasheet
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN2851335
Quantity 96 tests
Datasheet Datasheet

Recommended PTGR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124609
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316754
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3127519
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PTGR1 Products

Xue, Zhu, Wang, Li, Zhang, Wang, Chen, Chen, Chong: "Knockdown of prostaglandin reductase 1 (PTGR1) suppresses prostate cancer cell proliferation by inducing cell cycle arrest and apoptosis." in: Bioscience trends, Vol. 10, Issue 2, pp. 133-9, (2017) (PubMed).

Huang, Zhou, Zhang, Liu: "High Expression of PTGR1 Promotes NSCLC Cell Growth via Positive Regulation of Cyclin-Dependent Protein Kinase Complex." in: BioMed research international, Vol. 2016, pp. 5230642, (2017) (PubMed).

Yang, Luo, Wang, Mao, Chen, Wang, Guo: "Effect of prostaglandin reductase 1 (PTGR1) on gastric carcinoma using lentivirus-mediated system." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14493-9, (2016) (PubMed).

Vitturi, Chen, Woodcock, Salvatore, Bonacci, Koenitzer, Stewart, Wakabayashi, Kensler, Freeman, Schopfer: "Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25626-37, (2013) (PubMed).

Yu, Erzinger, Pietsch, Cervoni-Curet, Whang, Niederhuber, Sturla: "Up-regulation of human prostaglandin reductase 1 improves the efficacy of hydroxymethylacylfulvene, an antitumor chemotherapeutic agent." in: The Journal of pharmacology and experimental therapeutics, Vol. 343, Issue 2, pp. 426-33, (2012) (PubMed).

Zhai, Yang, Mancini, He, Antoniou, Di Battista: "Leukotriene B(4) BLT receptor signaling regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of Ras/Raf/ERK/p42 AUF1 pathway." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23568-80, (2010) (PubMed).

Synonyms and alternative names related to PTGR1

prostaglandin reductase 1 (PTGR1), prostaglandin reductase 1 (Ptgr1), prostaglandin reductase 1 (ptgr1), 2510002C21Rik, Dig1, LTB4DH, Ltb4dh, ltb4dh, PGR1, PTGR1, wu:fj35e05, ZADH3, zgc:101689

Protein level used designations for PTGR1

  • 15-oxoprostaglandin 13-reductase
  • NADP-dependent leukotriene B4 12-hydroxydehydrogenase
  • PRG-1
  • leukotriene B4 12-hydroxydehydrogenase
  • zinc binding alcohol dehydrogenase domain containing 3
  • D3T-inducible gene 1 protein
  • DIG-1
  • dithiolethione-inducible gene 1 protein
  • dithiolethione-inducible gene-1
  • NADP dependent leukotriene b4 12-hydroxydehydrogenase
  • prostaglandin reductase 1
  • ADRAB-F
  • 12-HD
  • LTB4
  • PGR
  • leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase
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