IL-33 蛋白
Quick Overview for IL-33 蛋白 (ABIN988078)
抗原
See all IL-33 (IL33) 蛋白生物活性
宿主
资源
纯度
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序列
- SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSK
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产品特性
- Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106units/mg.
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内毒素水平
- Level Less than 1EU/µg of rMuIL-33 as determined by LAL method
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
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储存条件
- 4 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- Interleukin-33 (IL-33)
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背景
- IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Mouse. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, EDTA and DTT, pH 7.4.
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分子量
- Approximately 17.5 kDa protein containing 158 amino acid residues.
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途径
- Production of Molecular Mediator of Immune Response
抗原
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