Purified recombinant Mouse MIP1 alpha protein Expression System: E.coli Bioactivity: Determined by its ability to chemoattract Mouse balb/c splenocytes using a concentration range of 10.0-100.0 ng/mL.
CCL3
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 97 % by SDS PAGE
CMA
Active
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
缓冲液
Supplied as a lyophilized powder.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
抗原
CCL3
(Chemokine (C-C Motif) Ligand 3 (CCL3))
别名
MIP1 alpha
背景
Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells. Alternative Names: CCL3 protein, MIP-1 alpha protein, MIP-1 alpha protein, MIP 1 alpha protein, MIP1 alpha, Macrophage Inflammatory Protein-1 alpha protein, LD78 alpha protein, MIP-1 alpha, MIP 1 alpha