CCL3 Protein (AA 24-92)
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- 抗原 See all CCL3 蛋白
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-92
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Cell Migration Assay (CMA)
- 序列
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
- 产品特性
- Recombinant Human CCL3 (MIP-1alpha)
- 纯度
- > 97 % by SDS PAGE
- 内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
- Top Product
- Discover our top product CCL3 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- 储存条件
- -20 °C,-80 °C
- 储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - 有效期
- 12 months
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- 抗原
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- 别名
- CCL3 (MIP-1alpha) (CCL3 产品)
- 别名
- MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
- 背景
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
- 分子量
- 7.716 kDa
- UniProt
- P10147
- 途径
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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