CCL3 蛋白
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北京 101111
Quick Overview for CCL3 蛋白 (ABIN935631)
抗原
See all CCL3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
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产品特性
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Purified recombinant Human MIP1 alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration of 50.0-100.0 ng/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
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别名
- MIP1 alpha
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背景
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Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
Alternative Names: MIP-1 alpha protein, LD78 beta protein, MIP 1 alpha, CCL3 protein, MIP 1 alpha protein, MIP-1 alpha protein, MIP-1 alpha, Macrophage Inflammatory Protein-1 alpha protein, MIP1 alpha -
分子量
- 7.8 kDa
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途径
- Cellular Response to Molecule of Bacterial Origin, Autophagy
抗原
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