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Epigen 蛋白

This Recombinant Epigen protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935330
发货至: 中国

Quick Overview for Epigen 蛋白 (ABIN935330)

抗原

See all Epigen (EPGN) 蛋白
Epigen (EPGN) (Epithelial Mitogen (EPGN))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

    产品特性

    Purified recombinant Human Epigen protein
    Expression System: E.coli
    Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Supplied as a lyophilized powder.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    Epigen (EPGN) (Epithelial Mitogen (EPGN))

    别名

    Epigen

    背景

    Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
    Alternative Names: EPG protein, Epithelial mitogen protein

    分子量

    7.9 kDa

    途径

    RTK signaling, EGFR Signaling Pathway
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