CD40 Protein (CD40)
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- 抗原 See all CD40 蛋白
- CD40
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
- 产品特性
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Purified recombinant Human CD40 protein
Expression System: E.coli - 纯度
- > 98 % pure
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product CD40 蛋白
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CD40 (CD40) (AA 21-193) protein (His-Avi Tag,Biotin)
CD40 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 21-193) protein (His tag)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 24-193) protein (His tag)CD40 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) protein (His tag)CD40 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD40 (CD40) (AA 21-193) protein (Fc Tag)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 21-193) protein (mFc-His Tag)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD40 (CD40) (AA 21-193) protein (His-DYKDDDDK-Strep II Tag)CD40 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD40 (CD40) (AA 24-193) (Active) protein (His tag)CD40 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD40 (CD40) (AA 21-193) (Active) protein (His tag)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD40 (CD40) (AA 21-193) (Active) protein (His tag)CD40 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 5-10 mM Na3PO4, pH 7.5 to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- Sterile filtered through a 0.2 μm filter. Lyophilized from 10 mM Na3PO4, pH 7.5.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- 抗原
- CD40
- 别名
- CD40 (CD40 产品)
- 背景
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CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L.
Alternative Names: soluble CD40 Ligand protein, CD-40 protein, CD-40, CD40, CD 40, TRAP protein, TNFSF5 protein, gp39 protein, T-BAM protein, CD154 protein, CD 40 protein - 分子量
- 16.3 kDa
- 途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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