PCNA Protein (AA 1-261)
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- 抗原 See all PCNA 蛋白
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-261
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S
- 产品特性
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Purified recombinant Human PCNA protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - 纯度
- > 95 % pure
- Top Product
- Discover our top product PCNA 蛋白
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- 应用备注
- PCNA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Supplied as a liquid in 20 mM Tris, pH 7.5, containing 0 mM EDTA, and 20 % glycerol.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
- 储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- 抗原
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
- 别名
- PCNA (PCNA 产品)
- 背景
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PCNA (Proliferating Cell Nuclear protein) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques.
Alternative Names: PCNA protein, , Proliferating cell nuclear protein protein, MGC8367 protein, Proliferating cell nuclear protein protein - 分子量
- 28 kDa (261 AA)
- 途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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