Quick Overview for SHP1 蛋白 (ABIN934896)
抗原
See all SHP1 (PTPN6) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
-
-
序列
- MGFWEEFESL QKQEVKNLHQ RLEGQRPENK GKNRYKNILP FDHSRVILQG RDSNIPGSDY INANYIKNQL LGPDENAKTY IASQGCLEAT VNDFWQMAWQ ENSRVIVMTT REVEKGRNKC VPYWPEVGMQ RAYGPYSVTN CGEHDTTEYK LRTLQVSPLD NGDLIREIWH YQYLSWPDHG VPSEPGGVLS FLDQINQRQE SLPHAGPIIV HCSAGIGRTG TIIVIDMLME NISTKGLDCD IDIQKTIQMV RAQRSGMVQT EAQYKFIYVA IAQFIETTKK KLEVLQSQKG QESEYGNITY
-
产品特性
-
Purified recombinant Human SHP1 protein
Expression System: E.coli
Bioactivity: >5,000units/mg of SHP-1
Molecular weight on SDS-PAGE will appear higher. -
内毒素水平
- < 1.0 EU per µg of protein (determined by LAL method)
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (His tag)
custom-made PTPN6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (His tag)custom-made PTPN6 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 5-163) protein (His-IF2DI Tag)PTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Protein-tyrosine Phosphatase 1C (PTPN6) proteinPTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597) protein (GST tag)PTPN6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA, PAA
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 207-597) (Active) protein (GST tag,His tag)PTPN6 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
-
-
应用备注
- SHP1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
-
说明
-
One unit will hydrolyze 1 nM of p-nitrophenyl- phosphatate(pNPP) per minute at pH 7.4 at 37 °C using 10 mM of substrate.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Supplied as a liquid in 25 mM Tris-HCl, pH7.5, containing 2 mM beta-mercaptoethanol, 1 mM EDTA.1 mMDTT, and 20 % glycerol.
-
储存液
- Dithiothreitol (DTT)
-
注意事项
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- RT/-20 °C
-
储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
-
-
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
-
别名
- SHP1
-
背景
-
The protein coding region of the catalytic domain of SHP-1 (amino acids 243-541) was cloned into an E. coli expression vector. The catalytic domain of SHP-1 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant SHP-1 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid(Met) is attached at N-terminus.
Alternative Names: Protein tyrosine phosphatase non-receptor type 6 isoform 1 protein, PTPN6 protein, SHP1, SHP 1 protein, SHP-1, Tyrosine-protein phosphatase non-receptor type 6 protein, Hematopoietic cell phosphatase protein, Hematopoietic cell protein tyrosine phosphatase protein, Protein tyrosine phosphatase SHP 1 protein, SHP-1 protein, HCP protein, HCPH protein, Protein-tyrosine phosphatase 1C protein, SHP 1, SHPTP 1 protein, HCP protein, SHP 1 protein, SH PTP1 protein, 70 kda SHP1L protein protein, SHP 1L protein, SH PTP 1 protein, SH-PTP1 protein, PTP1C protein, Protein-tyrosine phosphatase SHP-1 protein, PTP 1C protein, HPTP1C protein, Protein tyrosine phosphatase 1C protein, SHP1 protein, HPTP 1C protein, SHP-1L EC 3.1.3.48 protein, PTPN6 protein, Hematopoietic cell protein-tyrosine phosphatase protein, Protein tyrosine phosphatase SHP1 protein, Tyrosine protein phosphatase non receptor type 6, SHPTP1 protein, SHP1L protein, PTPN 6 protein, PTP-1C protein, EC 3.1.3.48 protein -
分子量
- 34.3 kDa (300 AA)
-
途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
抗原
-
