YAP1 蛋白
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北京 101111
Quick Overview for YAP1 蛋白 (ABIN7939761)
抗原
See all YAP1 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant YAP1 protein
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Yes-Associated Protein 1 (YAP1) (AA 1-504) protein (GST tag)
YAP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Yes-Associated Protein 1 (YAP1) (AA 53-161) protein (GST tag)YAP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Yes-Associated Protein 1 (YAP1) (AA 1-504) protein (His tag)YAP1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ScA, AM, ADA, IA
Yes-Associated Protein 1 (YAP1) (AA 350-504) protein (His tag)YAP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Yes-Associated Protein 1 (YAP1) (AA 1-504), (full length) protein (His tag)YAP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
Yes-Associated Protein 1 (YAP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)YAP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant YAP1 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- YAP1 (Yes-Associated Protein 1 (YAP1))
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别名
- YAP1
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背景
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Protein Background: YAP1 is a transcriptional regulator with dual roles as a coactivator and corepressor. Critical downstream regulatory target in the Hippo signaling pathway, crucial for organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The Hippo signaling pathway core involves a kinase cascade featuring STK3/MST2 and STK4/MST1, along with its regulatory partner SAV1, which phosphorylates and activates LATS1/2 in complex with their regulatory protein, MOB1. This activation leads to the phosphorylation and inactivation of the YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 prevents its nuclear translocation, thereby regulating the expression of its target genes.
Short Description: Recombinant YAP1 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_001181973.1) with an N-terminal FLAG tag. The molecular weight of YAP1 is 54.04 kDa.
Aliases: YAP65, YAP-1, Transcriptional Coactivator YAP1, Yes Associated Protein 1, COB1, YAP2, YAP, YKI
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途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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