CDK2 蛋白
Our Local Distributor
北京 101111
Quick Overview for CDK2 蛋白 (ABIN7938736)
抗原
See all CDK2 蛋白蛋白类型
宿主
资源
应用范围
-
-
原理
- Recombinant CDK2 protein
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Cyclin-Dependent Kinase 2 (CDK2) (AA 1-346) protein (His tag)
custom-made CDK2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) protein (His tag)custom-made CDK2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) protein (GST tag)CDK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) protein (His tag)CDK2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Recombinant CDK2 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
储存条件
- -80 °C
-
储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
-
别名
- CDK2
-
背景
-
Protein Background: CDK2 (Cyclin-dependent kinase 2) , also known as CDKN2 and p33(CDK2)CDKN2 is a serine/threonineprotein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. Phosphorylates CABLES1, CTNNB1, CDK2AP2, ERCC6, NBN, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis and modulates G2 progression, controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in embryonic stem cells (ESCs).
Short Description: Recombinant CDK2 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_001789.2) with an C-terminal FLAG tag. The molecular weight of CDK2 is 35.62 kDa.
Aliases: CDKN2, p33(CDK2), Cell Division Protein Kinase 2, P33(CDK2)
-
途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
-
