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IL-6 Receptor Protein (AA 20-358, Subunit alpha)

This Recombinant IL-6 Receptor protein is expressed in Insect cells (Sf21).
产品编号 ABIN7955874
发货至: 中国
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Quick Overview for IL-6 Receptor Protein (AA 20-358, Subunit alpha) (ABIN7955874)

抗原

See all IL-6 Receptor (IL6R) 蛋白
IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 20
  • 7
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  • 1

资源

  • 11
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Insect cells (Sf21)

纯度

> 97 % by SDS-PAGE analyses.
  • 产品特性

    AA 20-358, Subunit alpha

    原理

    Recombinant Human Interleukin-6 Receptor Subunit Alpha

    序列

    Leu20-Asp358,

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 1 EU/ug of rHuIL-6 Ralpha as determined by LAL method.

    Biological Activity Comment

    Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.
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  • 说明

    Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from 0.2 um filtered concentrated solution in PBS.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

    别名

    Interleukin-6 Receptor

    分子量

    50 kDa

    途径

    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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