IL-6 Receptor Protein (AA 20-358, Subunit alpha)
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Quick Overview for IL-6 Receptor Protein (AA 20-358, Subunit alpha) (ABIN7955874)
抗原
See all IL-6 Receptor (IL6R) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 20-358, Subunit alpha
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原理
- Recombinant Human Interleukin-6 Receptor Subunit Alpha
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序列
- Leu20-Asp358,
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 1 EU/ug of rHuIL-6 Ralpha as determined by LAL method.
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Biological Activity Comment
- Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.
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说明
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Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from 0.2 um filtered concentrated solution in PBS.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.
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有效期
- 12 months
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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别名
- Interleukin-6 Receptor
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分子量
- 50 kDa
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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