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M-CSF/CSF1 蛋白

This Recombinant M-CSF/CSF1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7866445
发货至: 中国
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Quick Overview for M-CSF/CSF1 蛋白 (ABIN7866445)

抗原

See all M-CSF/CSF1 (CSF1) 蛋白
M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE
  • 原理

    Recombinant Human M-CSF Protein

    序列

    MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS

    特异性

    Chromosomal location:1p21-p13

    产品特性

    Length (aa):159

    内毒素水平

    < 0.1 ng/μg of protein (< 1EU/μg)
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  • 应用备注

    The biological activity was determined by the dose-dependent induction of proliferation in NFS60 cells (Murine myeloid Leukemia cell line).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    water

    缓冲液

    PBS
  • 抗原

    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

    别名

    M-CSF

    背景

    Synonyms: CSF1, MCSF, CSF-1

    Description: Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E. coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 36.8 KD. M-CSF is purified by proprietary chromatographic techniques.

    分子量

    36.8 kDa

    基因ID

    1435

    NCBI登录号

    NM_000757, NP_000748

    UniProt

    P09603

    途径

    RTK signaling
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