M-CSF/CSF1 蛋白
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北京 101111
Quick Overview for M-CSF/CSF1 蛋白 (ABIN7866444)
抗原
See all M-CSF/CSF1 (CSF1) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human M-CSF Protein
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序列
- MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
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特异性
- Chromosomal location:1p21-p13
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产品特性
- Length (aa):159
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内毒素水平
- < 0.1 ng/μg of protein (< 1EU/μg)
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应用备注
- The biological activity was determined by the dose-dependent induction of proliferation in NFS60 cells (Murine myeloid Leukemia cell line).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- water
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缓冲液
- PBS
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- M-CSF
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背景
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Synonyms: CSF1, MCSF, CSF-1
Description: Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E. coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 36.8 KD. M-CSF is purified by proprietary chromatographic techniques.
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分子量
- 36.8 kDa
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基因ID
- 1435
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NCBI登录号
- NM_000757, NP_000748
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UniProt
- P09603
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途径
- RTK signaling
抗原
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