IGF1 蛋白
Quick Overview for IGF1 蛋白 (ABIN7680475)
抗原
See all IGF1 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
质量等级
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原理
- rIGF-1 LR3 - Recombinant human Insulin-like growth factor-1 LR3
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产品特性
- This product arrives as White lyophilized powder
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内毒素水平
- Less than 5 EU/mg
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Biological Activity Comment
- The bioactivity determined by a cell proliferation assay using Balb/c 3T3 cell, corresponding to a specific activity of ≥ 1x10^6 Units/mg.
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Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) (Active) protein
IGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Insulin-Like Growth Factor 1 (IGF1) (Active) proteinIGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor 1 (IGF1) (Active) proteinIGF1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) protein (His-IF2DI Tag)IGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) (Active) protein (His tag)IGF1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Insulin-Like Growth Factor 1 (IGF1) (AA 49-138) protein (GST tag)IGF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Insulin-Like Growth Factor 1 (IGF1) protein (Fc Tag)IGF1 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor 1 (IGF1) protein (Fc Tag)IGF1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor 1 (IGF1) (AA 1-153) protein (GST tag)IGF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Insulin-Like Growth Factor 1 (IGF1) (AA 1-115) (Active) proteinIGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended to reconstitute LR3 IGF-1 at 100-200 μg/mL in sterile water.
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缓冲液
- It is lyophilized with mannitol as the stabilizer.
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注意事项
- Use as soon as possible after opening. Avoid freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Stored at temperatures -20°C for at least 36 months. Further dilutions can be made in other aqueous buffer. Use as soon as possible after opening. Please avoid freeze-thaw cycles.
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有效期
- 36 months
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- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
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别名
- Insulin-like growth factor-1
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背景
- Insulin-like growth factor-1 (IGF-1) is a hormone similar in molecular structure to insulin. It primarily functions through binding to its specific receptor, the insulin-like growth factor 1 receptor (IGF1R). IGF-1 is one of the most potent natural activators of the AKT signaling pathway, which stimulates cell growth and proliferation, and inhibits cell apoptosis. LR3 IGF-1 (Long Arg3 IGF-1) is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus. The LR3 IGF-1 has much higher stability and biological activity.
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分子量
- 9.1kD
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途径
- RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
抗原
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