CSK Protein (His-GST)
Quick Overview for CSK Protein (His-GST) (ABIN7668268)
抗原
See all CSK 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CSK protein is labelled with His-GST.
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原理
- Recombinant Human SRC Kinase/c-SRC Protein (His & GST Tag)
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序列
- Met 1-Leu 536
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纯化方法
- > 90 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be > 80 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
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C-Src tyrosine Kinase (CSK) (AA 1-450) protein (GST tag)
CSK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
C-Src tyrosine Kinase (CSK) (Active) protein (GST tag,His tag)CSK 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
C-Src tyrosine Kinase (CSK) (Active) protein (GST tag)CSK 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
C-Src tyrosine Kinase (CSK) proteinCSK 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
C-Src tyrosine Kinase (CSK) (AA 1-450) protein (His tag)CSK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95% by SDS-PAGE SDS
C-Src tyrosine Kinase (CSK) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)CSK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 50 mM Tris, 100 mM NaCl, pH 8.0, 20 % glycerol, 0.3 mM DTT
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CSK (C-Src tyrosine Kinase (CSK))
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别名
- SRC Kinase
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背景
- Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.,ASV,SRC1,c-SRC,p60-Src
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分子量
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calculated_mw: 87.7 kDa
observed_mw: 81 kDa
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UniProt
- P12931
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途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
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