Nanog Protein (AA 1-305) (His tag)
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北京 101111
Quick Overview for Nanog Protein (AA 1-305) (His tag) (ABIN7554668)
抗原
See all Nanog (NANOG) 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-305
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标记
- This Nanog protein is labelled with His tag.
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原理
- Predefined custom protein recombinant NANOG Protein expressed in mammalian cells.
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序列
- MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 Escherichia coli (E. coli)Conjugate His-IF2DI TagOrigin HumanPrice 5,093.31 ¥表达系统 Escherichia coli (E. coli)ConjugateOrigin HumanPrice 6,868.77 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 7,646.38 ¥表达系统 Escherichia coli (E. coli)ConjugateOrigin HumanPrice 22,519.46 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 1,936.84 ¥表达系统 Escherichia coli (E. coli)Conjugate His-IF2DI TagOrigin HumanPrice 5,093.31 ¥表达系统 Escherichia coli (E. coli)Conjugate His tag,GST tagOrigin HumanPrice 7,720.01 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 17,973.45 ¥表达系统 Escherichia coli (E. coli)Conjugate TAT tagOrigin HumanPrice 4,400.78 ¥表达系统 Escherichia coli (E. coli)Conjugate TAT tagOrigin HumanPrice 4,171.14 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Nanog Homeobox (NANOG) (AA 1-305) protein (His tag)
custom-made NANOG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nanog Homeobox (NANOG) (AA 2-305) protein (His-IF2DI Tag)NANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % SDS
Nanog Homeobox (NANOG) (AA 1-154) protein (His tag)NANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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别名
- NANOG
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背景
- Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog),FUNCTION: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Binds to the POU5F1/OCT4 promoter (PubMed:25825768). Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation. {ECO:0000269|PubMed:15983365, ECO:0000269|PubMed:16000880, ECO:0000269|PubMed:16391521, ECO:0000269|PubMed:25825768}.
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分子量
- 34.6 kDa
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UniProt
- Q9H9S0
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AlphaFold
- Q9H9S0
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途径
- Stem Cell Maintenance
抗原
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