Nanog Protein (TAT tag)
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- 抗原 See all Nanog (NANOG) 蛋白
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Nanog protein is labelled with TAT tag.
- 序列
- MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA ENSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDVGGYGR KKRRQRRR
- 产品特性
- Endotoxin level is less than 0.1 ng per ug (1EU/μg).
- 纯度
- < 95 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per ug (1 EU/μg).
- Top Product
- Discover our top product NANOG 蛋白
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Nanog Homeobox (NANOG) (AA 1-305) protein
NANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % by SDS - PAGE SDS
Nanog Homeobox (NANOG) (AA 2-305) protein (His tag)NANOG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nanog Homeobox (NANOG) (AA 98-195) protein (GST tag)NANOG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Nanog Homeobox (NANOG) (AA 1-305) protein (Strep Tag)Crystallography grade NANOG 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Nanog Homeobox (NANOG) (AA 1-305) protein (Strep Tag)Crystallography grade NANOG 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing Nanog-TAT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Nanog-TAT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- 别名
- Nanog (NANOG 产品)
- 别名
- 2410002E02Rik Protein, ENK Protein, ecat4 Protein, NANOG Protein, hacp Protein, wu:fd19e04 Protein, wu:fd20a07 Protein, zgc:193933 Protein, Nanog homeobox Protein, nanog homeobox Protein, Nanog Protein, NANOG Protein, nanog Protein
- 背景
- Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which helps maintain pluripotency and self renewal via a STAT3 independent pathway. The introduction of Nanog, along with Sox2, Oct4, Lin28, into primary human fibroblasts was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology and gene expression. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant human Nanog-TAT is a 36.2 kDa protein, which is synthesized as a 304 amino acid polypeptide plus a 13- residue C-terminal TAT peptide.
- 基因ID
- 388112
- OMIM
- 74762336
- UniProt
- Q6NSW7
- 途径
- Stem Cell Maintenance
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