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Nanog Protein (AA 94-162) (His tag)

This Recombinant Nanog protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7505155
发货至: 中国
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Quick Overview for Nanog Protein (AA 94-162) (His tag) (ABIN7505155)

抗原

See all Nanog (NANOG) 蛋白
Nanog (NANOG) (Nanog Homeobox (NANOG))

蛋白类型

Recombinant

宿主

  • 11
  • 2
  • 1
  • 1

资源

  • 9
  • 2
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  • 2
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 94-162

    标记

    This Nanog protein is labelled with His tag.

    序列

    Lys 94-Ser 162

    产品特性

    A DNA sequence encoding the Human NANOG protein (Q9H9S0) (Lys 94-Ser 162) was expressed with a N-His tag.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 127,054.94 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    NANOG

    背景

    Abbreviation: NANOG

    Target Synonym: Embryonic stem cell specific homeobox protein,ENK,FLJ12581,hNanog,Homeobox protein NANOG

    Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation.

    分子量

    Calculated MW: 7.48 kDa

    Observed MW: 12 kDa

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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