Muscarinic Acetylcholine Receptor M2 Protein (AA 1-466) (His tag)
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- 抗原 See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 蛋白
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-466
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Muscarinic Acetylcholine Receptor M2 protein is labelled with His tag.
- 原理
- Predefined custom protein recombinant CHRM2 Protein expressed in mammalian cells.
- 序列
- MNNSTNSSNN SLALTSPYKT FEVVFIVLVA GSLSLVTIIG NILVMVSIKV NRHLQTVNNY FLFSLACADL IIGVFSMNLY TLYTVIGYWP LGPVVCDLWL ALDYVVSNAS VMNLLIISFD RYFCVTKPLT YPVKRTTKMA GMMIAAAWVL SFILWAPAIL FWQFIVGVRT VEDGECYIQF FSNAAVTFGT AIAAFYLPVI IMTVLYWHIS RASKSRIKKD KKEPVANQDP VSPSLVQGRI VKPNNNNMPS SDDGLEHNKI QNGKAPRDPV TENCVQGEEK ESSNDSTSVS AVASNMRDDE ITQDENTVST SLGHSKDENS KQTCIRIGTK TPKSDSCTPT NTTVEVVGSS GQNGDEKQNI VARKIVKMTK QPAKKKPPPS REKKVTRTIL AILLAFIITW APYNVMVLIN TFCAPCIPNT VWTIGYWLCY INSTINPACY ALCNATFKKT FKHLLMCHYK NIGATR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product CHRM2 蛋白
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想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 Wheat germConjugate GST tagOrigin HumanPrice 5,094.84 ¥表达系统 HEK-293 CellsConjugate Fc TagOrigin HumanPrice 6,504.59 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 5,147.74 ¥表达系统 Wheat germConjugateOrigin HumanPrice 7,467.03 ¥表达系统 HEK-293 CellsConjugate DYKDDDDK Tag,Strep TagOrigin HumanPrice 10,523.52 ¥表达系统 HEK-293 CellsConjugateOrigin HumanPrice 75,751.22 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 1-466) protein (His tag)
custom-made CHRM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 251-350) protein (GST tag)CHRM2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Cholinergic Receptor, Muscarinic 2 (CHRM2) (AA 1-22) protein (Fc Tag)CHRM2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- 别名
- CHRM2 (CHRM2 产品)
- 背景
- Muscarinic acetylcholine receptor M2,FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3), this then triggers calcium ion release into the cytosol. {ECO:0000269|PubMed:24256733, ECO:0000269|PubMed:3443095}.
- 分子量
- 51.7 kDa
- UniProt
- P08172
- AlphaFold
- P08172
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