FASL Protein (AA 1-281) (His tag)
Quick Overview for FASL Protein (AA 1-281) (His tag) (ABIN7544498)
抗原
See all FASL 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-281
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标记
- This FASL protein is labelled with His tag.
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原理
- Predefined custom protein recombinant FASLG Protein expressed in mammalian cells.
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序列
- MQQPFNYPYP QIYWVDSSAS SPWAPPGTVL PCPTSVPRRP GQRRPPPPPP PPPLPPPPPP PPLPPLPLPP LKKRGNHSTG LCLLVMFFMV LVALVGLGLG MFQLFHLQKE LAELRESTSQ MHTASSLEKQ IGHPSPPPEK KELRKVAHLT GKSNSRSMPL EWEDTYGIVL LSGVKYKKGG LVINETGLYF VYSKVYFRGQ SCNNLPLSHK VYMRNSKYPQ DLVMMEGKMM SYCTTGQMWA RSSYLGAVFN LTSADHLYVN VSELSLVNFE ESQTFFGLYK L Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 HEK-293 CellsConjugate His tagOrigin HumanPrice 5,037.55 ¥表达系统 HEK-293 CellsConjugate Fc TagOrigin HumanPrice 9,035.75 ¥表达系统 Wheat germConjugate GST tagOrigin HumanPrice 6,623.29 ¥表达系统 Escherichia coli (E. coli)ConjugateOrigin HumanPrice 20,381.36 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 5,593.03 ¥表达系统 HEK-293 CellsConjugate DYKDDDDK TagOrigin Human, MousePrice 7,413.12 ¥表达系统 Wheat germConjugateOrigin HumanPrice 9,707.14 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 7,353.65 ¥表达系统 Escherichia coli (E. coli)Conjugate His tag,GST tagOrigin HumanPrice 7,353.65 ¥表达系统 HEK-293 CellsConjugate His tagOrigin HumanPrice 8,592.48 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-279) protein (His tag)
custom-made FASL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 134-281) (Active) protein (His tag)FASL 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fas Ligand (TNF Superfamily, Member 6) (FASL) protein (Fc Tag)FASL 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (GST tag)FASL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fas Ligand (TNF Superfamily, Member 6) (FASL) proteinFASL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- FASLG
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背景
- Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL), ADAM10-processed FasL form (APL), FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)],FUNCTION: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260). {ECO:0000250|UniProtKB:P41047, ECO:0000269|PubMed:17557115, ECO:0000269|PubMed:27806260, ECO:0000269|PubMed:7528780, ECO:0000269|PubMed:9228058, ECO:0000269|PubMed:9427603}., FUNCTION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways (By similarity). Can induce apoptosis but does not appear to be essential for this process (PubMed:27806260). {ECO:0000250|UniProtKB:P41047, ECO:0000269|PubMed:27806260}., FUNCTION: [FasL intracellular domain]: Cytoplasmic form induces gene transcription inhibition. {ECO:0000269|PubMed:17557115}.
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分子量
- 31.5 kDa
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UniProt
- P48023
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AlphaFold
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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